New ECCO CD guidelines. Hugely proud to have led with @HannahGordon Pär Myrelid @MichelAdaminamassive team effort from >50 clinicians, patients & methodologists representing 19 countries& 4 continents. A thread on what we did &why it does (&doesn’t) matter. doi.org/10.1093/ecco-j…

#Epigenetic #Fingerprints in IBD: From #Methylation Patterns to Clinical Implications Bram Verstockt IBD Leuven academic.oup.com/ecco-jcc/advan…

Presenilins: the hidden guardians of gut health in Alzheimer’s disease gut.bmj.com/content/early/… Gut Journal #JSchwärzler

🤔 Did you know? Each time FIBROTARGET publishes a scientific article, we'll break it down into 5 major components for a better understanding. We'll also create a visual Glossary of Terms so patients and citizens can learn more about what's happening fibrotarget.eu/scientific-pub…

Lemann Index #LI for assessing #bowel #damage in #CD: a real world study by Eric Prado Parakkal Deepak MD, MS, FACG Ryan Ungaro MD MS Jean-Frederic Colombel academic.oup.com/ecco-jcc/advan…

Early #IUS in severe ulcerative colitis identifies patients at increased risk of 1-year treatment failure and colectomy Ilvemark et al. Rune Wilkens Jakob Seidelin Trine Boysen academic.oup.com/ecco-jcc/advan…

Ileal Paneth Cell Phenotype is a Cellular Biomarker for #Pouch Complications in #UC Ma et al. academic.oup.com/ecco-jcc/advan…

Early life #Environmental factors assoc. w #Young #IBD Dx in Hispanics & Non-Hispanic Whites ✅C/section, birth in a developed country, >1🚽🚿at home (💡hygiene hypothesis/microbiome diversity?) ✅Plastic water bottle (💡microplastics & PFAS?) CGH doi.org/10.1016/j.cgh.…

#VIBRATO’s Symphony: Orchestrating Biomarker Harmony for #Ritlecitinib in #UC Therapy 🎵 Bram Verstockt IBD Leuven academic.oup.com/ecco-jcc/advan…

This work was only possible by the great support of the IBD Leuven FWO FIBROTARGET Boehringer Ingelheim and the dedication of Saeed and @bojunke Soon out in Journal of Clinical Investigation hopefully this will allow new targets selection for treatment of patients with IBD

Classifying Inflammation on Intestinal Ultrasound Images and Cineloops – A Learning Curve Study. Gorm Roager Madsen et al. Kerri Rune Wilkens InternationalBowelUS academic.oup.com/ecco-jcc/advan…

Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in @CD, a fantastic collaboration with Gianluca Matteoli with first authors Bo-Jun Ke Saeed now in Journal of Clinical Investigation jci.org/articles/view/… Severine Vermeire

Personal View of the Journey from Questions to Recommendations by Tim Raine Pär Myrelid #HGordon Michel Adamina "We hope the ECCO treatment guidelines remain a valuable point of reference for the contemporary management of IBD." academic.oup.com/ecco-jcc/advan…

Discordant effects of #JAK ex-vivo on inflammatory responses in colonic compared to ileal mucosa Kaboub et al. Idan Goren iris dotan Jacob Ollech Henit Yanai academic.oup.com/ecco-jcc/advan…

A proinflammatory role for #eosinophils in colitis, warranting further investigation into eosinophil targeting as a treatment option for patients with #IBD. Inge Jacobs et al. Bram Verstockt Tim Vanuytsel Sara D Severine Vermeire academic.oup.com/ibdjournal/adv…

Where innovation crosses boundaries! Final countdown has started! If you haven’t registered yet, register today! Looking forward welcoming you soon in Leuven for our International Congress! IBD Leuven Severine Vermeire João Sabino andre dhoore Gabriele Bislenghi ibdleuven2024.com

#Preoperative #optimization: nutritional assessment and strategies in IBD Julie Vanderstappen Sien Hoekx João Sabino Bram Verstockt andre dhoore Gabriele Bislenghi now in #Cophar sciencedirect.com/science/articl…

The Impact of #PAD4-dependent Neutrophil Extracellular Trap #NAT Formation on the Early Development of Intestinal #Fibrosis in #CD Gabriele Dragoni Severine Vermeire Bo-Jun Ke @tommaso_innocenti Gianluca Matteoli Bram Verstockt andre dhoore Gabriele Bislenghi academic.oup.com/ecco-jcc/advan…

Efficacy of mutant & engineered high acetate-producing S boulardii strains in a DSS-induced colitis model by Sara D Severine Vermeire @Raeslab Inge Jacobs Sare Verstockt Bram Verstockt Kaline Arnauts Gianluca Matteoli mdpi.com/2072-6643/16/1…

The deadline to register to our #Congress is just around the corner. You've got only a few days left, as the deadline is September 2nd. Detailed information available on the conference website ibdleuven2024.com. Be welcome and enjoy an engaging meeting !