Heart #organoids simulate congenital heart disease caused by pregestational diabetes. Read more in StemCellReports: cell.com/stem-cell-repo… Aitor Aguirre

biotechniques.com/cell-and-tissu…

Erm, how did Figure 1 get past a peer reviewer?! frontiersin.org/articles/10.33… H/T Dr Anna Young 💙

msutoday.msu.edu/news/2024/msu-…

Using donated pluripotent stem cells from adults, Aitor Aguirre, Aleksandra Kostina, Yonatan R. Lewis-Israeli, & their IQ team developed these highly accurate, mini human heart organoids to study human heart development and congenital heart disease. #HeartMonth

A human heart organoid system developed at @MichiganStateU can simulate embryonic heart development under pregestational diabetes-like conditions, offering a new way for researchers to study congenital heart defects without the need for animal models. bit.ly/3OHL09o #NIH

New research describes how heart organoids can be used for disease modeling of congenital heart defects. The technique mimics aspects of gestation by adding specific metabolic and hormonal factors to make a more physiological relevant mini heart in a dish bit.ly/46QYCVS

Join us this summer in beatiful Holland, MI, for the Great Lakes Advanced Molecular Summer Course in Stem Cell and Organoid Biology:

The Pinwheel Galaxy (M 101) as seen few nights ago from my backyard, ~21 million light-years away.

Optimizing Organoid Culture for Development and Disease Modeling the-scientist.com/optimizing-org…

Engineering mini human hearts to study pregnancy complications and birth defects theconversation.com/engineering-mi… via The Conversation U.S.

Congrats to Drs. @renzoloyaga and Daniel maximiliano for being awarded one of the 2024 Cardiovascular Research HVI-Pilot grants for the project "Identifying Molecular Pathways of responsiveness to GDMT in HFrEF, using patient-specific cardiac organoids." 🎉 @MSU

Wonderful time at the Great Lakes Molecular Sciences Course in #StemCells & #Organoids. Taught some, learned a lot & made new friends. Thanks to the organizers IQ Aitor Aguirre Christopher Contag! #SpartansWill amy ralston 👩‍🔬 Owen Tamplin Bin Gu David Jones MSU College of Human Medicine MSU

Today, we have good news! Our lab was awarded an NSF grant to explore applications of AI to iPSC-derived cardiomyocyte maturation and organoids in collaboration with Dr. John Zhang at Dartmouth College. Looking forward to exploring this rapidly evolving space!

Today, we also have good news. The Alternatives Research and Development Foundation (ARDF) has funded our project to develop heart organoid-based models for studying human atrial fibrillation. Many thanks to ARDF for their support!

The Department of Biomedical Engineering at Michigan State University is looking for a new Chair, follow this link if you are interested: careers.msu.edu/en-us/job/5200…