New bioRxiv from our lab by Qian Shao on a covalent 14-3-3 molecular glue with the transcription factors YAP and TAZ and using this glue as a 14-3-3 recruiter to sequester nuclear neo-substrates into the cytosol! Thanks to #AppleTreePartners & @themarkfdn
Excited to present our newest paper in J. Am. Chem. Soc. by Qian Shao on using a novel covalent molecular glue of 14-3-3 and ER/YAP/TAZ as a 14-3-3 recruiter for targeted protein localization of nuclear neo-substrates into the cytosol as a new induced proximity approach.