Guess who's back? Genome Science 2024 is coming to Bristol July 16 - 18! Sign up here: bristol.genomescience.org.uk

New manuscript from the lab "Hijackers, hitchhikers, or co-drivers? The mysteries of microbial mobilizable genetic elements”. Many (most?) mobile genetic elements (hitchers) depend on helpers to transfer, which raises many mysteries(1/n) doi.org/10.32942/X2R89M

SMBE pangenomes meeting details Dates: 26-28th November 2024. Location: National Museum of Nature and Science, Ueno Park, Tokyo, Japan. Abstract submission: 1st June-31st August. Registration: 1st July-31st October. See the updated website: smbepangenomes.bacpop.org

Promoter recruitment drives the emergence of proto-genes in a long-term evolution experiment with Escherichia coli Md. Hassan uz-Zaman, Simon D’Alton, Jeffrey E. Barrick, Howard Ochman journals.plos.org/plosbiology/ar… #LTEE #science #evolution #genetics #genomics #microbiology

Why do pangenomes vary so much across bacteria? 🦠🧬 We show that bacterial lifestyle is the key factor shaping pangenome fluidity. Read more in our paper out now in PNAS: doi.org/10.1073/pnas.2… With Chunhui Hao Dr Laurie Belcher Melanie Ghoul Stuart West

In @elife: A direct experimental test of Ohno’s hypothesis doi.org/10.7554/eLife.… So rare to get a ‘fundamental’ assessment at @elife but this paper deserves it! Also don’t miss the most excellent perspective article that puts this work into context: doi.org/10.7554/eLife.…

I’m excited to share our work Estimating between-country migration in pneumococcal populations academic.oup.com/g3journal/arti… out now in G3 Genetics Society of America 1/9

First paper from my student Daria Frolova's PhD now on biorxiv: biorxiv.org/content/10.110… The key question: plasmids change structurally ~as fast as they mutate, so how can we decide whether 2 plasmids are "the same plasmid" for epi purposes? 1/n

Our new collaborative work in Science Magazine led by talia🌻 between my lab UCL Biosciences CLOE: UCL Centre for Life's Origins and Evolution Max Planck Institute for Biology Tübingen UCL Faculty of Life Sciences & the Karasov Lab University of Utah School of Biological Sciences (tkarasovlab.org) tinyurl.com/y85b2xn9

Very pleased to say that our preprint investigating CRISPR-Cas9 enrichment of Enterobacterales pathogens is now public! We enriched for tRNA, MLST, AMR and integron genes and sequenced on Oxford Nanopore platforms (1/8). biorxiv.org/content/10.110…

Published today in Evolution Letters 🎉🎉 Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade bacteria from the respiratory microbiome academic.oup.com/evlett/article… A short thread 🧵:

A thread.. Thrilled this is published in nature! We quantified the geographic spread of S.pneumo and estimated fitness changes of strains. Stephen Bentley launched the "migration concept"- I thought it was possible with GlobalPneumoSeq then we brought in Henrik Salje Noémie Lefrancq

The varicella vaccine was developed in the 1970s and introduced to the standard immunisation programme including the US in 1995. So, why has England only just made the recommendation? Read our latest blog by PhD student, Lauren Adams, to find out! cph.cam.ac.uk/resources/blog…

There were hypotheses about the potential drivers of the 22-23 upsurge of scarlet fever and deaths from invasive StrepA, but something was missing. Read our blog from Jenny Hall on the investigation here👇microb.io/3WLDIV9 Molecular Microbiology Sheffield Claire Turner The Florey Institute

We are hiring! We have an MRC-funded Post-doctoral Research Fellow position available, studying barriers to horizontal gene transfer of AMR genes in MRSA. jobs.sgul.ac.uk/632-24

Register now to attend our final Roadshow of the year! Find out about publishing with us from the journal’s Editors, such as Lucy Weinert (Cambridge University). Our Microbial Genomics Roadshow is taking place on 11 November in Oxford - microb.io/46dQnEu #MGen #MicrobioRoadshow

Congrats 🙌🏽

We are running a massive online open course on AMR databases starting end of the month. Its completely free, study at your own pace and its ~15 hours overall over the 3 weeks (although you can finish any time in a year). Please spread in your networks! …erences.wellcomeconnectingscience.org/event/antimicr…