H. Jack West, MD, FASCO (@jackwestmd) 's Twitter Profile
H. Jack West, MD, FASCO

@jackwestmd

VP of Clin Development, @SMMT_Tx; Founder,@CancerGRACE; fmr author/ed @UptoDate, fmr Web Ed @JAMAOnc & @MedscapeOnc columnist; Likes/RTs ≠ endorsement

ID: 28943421

linkhttp://www.JackWestMD.com calendar_today05-04-2009 04:54:07

27,27K Tweet

22,22K Followers

2,2K Following

GRACE (@cancergrace) 's Twitter Profile Photo

For 18 years, we’ve been your trusted partner in the fight against cancer. Our steadfast mission is to provide accessible, expert-mediated information on current and emerging cancer management options to empower patients, caregivers, and health professionals to become direct

JAMA Oncology (@jamaonc) 's Twitter Profile Photo

Progression-free survival and overall survival benefits of adding chemotherapy to gefitinib were sustained at 5 years, confirming earlier results reported at median follow-up of 17 months. ja.ma/3xOx344

Progression-free survival and overall survival benefits of adding chemotherapy to gefitinib were sustained at 5 years, confirming earlier results reported at median follow-up of 17 months. ja.ma/3xOx344
LARVOL (@larvol) 's Twitter Profile Photo

We’re thrilled to share the Top 20 Voices in Lung Cancer on X, as chosen by their peers. 💫 These dedicated individuals are making a real impact in raising awareness, supporting patients, and driving research forward. Thank you for your tireless efforts and commitment. A

H. Jack West, MD, FASCO (@jackwestmd) 's Twitter Profile Photo

Benefit of WFH: At risk of being judged for frugality (or being cheap), I'll confess I now have several shirts w/a hole, permanent stain, fraying around collar, missing buttons, etc that are still suitable for zoom/Teams calls because offending problem isn't visible on camera.🤩

H. Jack West, MD, FASCO (@jackwestmd) 's Twitter Profile Photo

Riddle me this, Batman: why was contribution of phase not a prohibitive issue w/approval of pembro based on the KEYNOTE-671 trial but is now a critical factor for other trials with same design for same setting? 🤯

H. Jack West, MD, FASCO (@jackwestmd) 's Twitter Profile Photo

So, people with more aggressive cancer have worse outcomes... Perhaps it has less to do with the treatment pursued than the underlying biology of the cancer.

H. Jack West, MD, FASCO (@jackwestmd) 's Twitter Profile Photo

Appreciate need for clarity, but problematic when decision occurs after approval < 1 yr ago of pembro based on KN-671, w/same problematic design. Can U.S. FDA define which phase was critical in KN-671? Why didn't this issue come up before that decision?

Aakash Desai, MD, MPH (@adesaimd) 's Twitter Profile Photo

H. Jack West, MD, FASCO U.S. FDA Yes absolutely, that’s the obvious question. I heard a comment saying “We did something before, doesn’t mean we need to do the same mistake again” Regardless, this will come up again with 77T and still may end up with the same fate- then I 🤔what was the point of the ODAC?

H. Jack West, MD, FASCO (@jackwestmd) 's Twitter Profile Photo

Esp when FDA says they will stop other trials from proceeding, optics look bad when they approve some agents in same setting based on trials they will now prohibit, & when these issues were clear before any of these approvals. Suggests different rules exist for diff companies.

Bishal Gyawali (@oncology_bg) 's Twitter Profile Photo

BIG ANNOUNCEMENT! Skills Lab: Interpreting Clinical Research with Bishal Gyawali is now live Medscape Medscape Oncology ! Join me for a Series of Videos (with Transcripts) on how to interpret clinical research. I am super excited about this series where I can share with the audience

BIG ANNOUNCEMENT! Skills Lab: Interpreting Clinical Research with Bishal Gyawali is now live <a href="/Medscape/">Medscape</a> <a href="/MedscapeOnc/">Medscape Oncology</a> ! Join me for a Series of Videos (with Transcripts) on how to interpret clinical research. I am super excited about this series where I can share with the audience
Gavin Preston, M.D. (@gavinprestonmd) 's Twitter Profile Photo

Medicine is the profession where when the canary in the coal mine dies, administrators just exclaim-- "Why can't we find more resilient canaries?"

Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

#WCLC24 abstract titles released! Don't miss the plenary Sunday September 8th at 8:30am PDT - I am particularly eager to see the ivonescimab vs pembro HARMONi-2 data from Dr. Caicun Zhou, Neocoast-2 from Dr. Tina Cascone, and the 77T vs CM816 analysis from Dr. Patrick Forde!

#WCLC24 abstract titles released! Don't miss the plenary Sunday September 8th at 8:30am PDT - I am particularly eager to see the ivonescimab vs pembro HARMONi-2 data from Dr. Caicun Zhou, Neocoast-2 from Dr. Tina Cascone, and the 77T vs CM816 analysis from Dr. <a href="/FordePatrick/">Patrick Forde</a>!
H. Jack West, MD, FASCO (@jackwestmd) 's Twitter Profile Photo

Will this actually change practice for anyone? If people are already doing neoadjuvant chemo/nivo or peri-operative chemo/pembro f/b pembro post-op, is anyone switching to AEGEAN regimen? If so, what is driving that?